Last update on 3 May 2013 by Dr Cécile Loï

Muscle loss associated with aging


Muscle loss starts early. Muscle tissue undergoes a slow degeneration of the order of 3 to 8% per decade in favor of fat since the age of 301. Thus, between 20 and 30 years, the percentage of muscle mass represents 30% of body mass and represents only 17% at 70 years old. Finally, between 25 and 75 years, muscle mass decreases by half !

When muscle loss reaches a certain level, it leads to a pathology : the sarcopenia2.

Preserving muscle mass throughout his life and detect muscle loss seem essential to promote successful aging.


References :

1. Munro HN. Adaptation of body protein metabolism in adult and aging man. Clin.Nutr. 1982;1:95‑108.

2. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al. Sarcopenia: European Consensus on Definition and Diagnosis Report of the European Working Group on Sarcopenia in Older People. Age Ageing. 7 janv 2010;39(4):412‑423.

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